The disease results from an attack by the bodys own immune system, causing inflammation in the walls of arteries. Takayasu described the retinal changes of the disease in 1905 at the annual ophthalmology society meeting in japan, and his abstract was subsequently published in 1908. Takayasus arteritis is a chronic inflammatory condition that affects the largest blood vessel in the body the aorta and its branches. It is also known as takayasu s aortitis, pulseless disease and aortic arch syndrome. Takayasus arteritis is a chronic vasculitis of unkown origin. Ta ziekte van takayasu takayasu arteritis vasculitis stichting. Takayasu, arteritis, vasculitis, aorta, large vessel, children. Takayasuarteritis arteritis, takayasu pulseless disease. Takayasu arteritis is a well known yet rare form of large vessel vasculitis. Mycophenolate mofetil for the treatment of takayasu arteritis. Tiene amplia distribucion mundial, con gran prevalencia en asia 6. Takayasus arteritis american college of rheumatology.
Takayasu arteritis ta, also known as idiopathic medial aortopathy or pulseless disease, is a granulomatous large vessel vasculitis that predominantly affects the aorta and its major branches. Takayasus arteritis ta is a chronic inflammatory disease of unknown. Aug 11, 2011 takayasu arteritis is an autoimmune vasculitis that affects the large and medium vessels. Takayasus arteritis, also called tak, is a rare form of vasculitis disease involving inflammation in the walls of the largest arteries in the body. Takayasu arteritis has long been considered as an uncommon disease, rather specific to the fareast. The aorta and its branches are mainly involved and stenosis or. The exact cause is not well known but the pathology is thought to be similar to giant cell arteritis. Takayasus arteritis ta is a rare chronic inflammatory arteritis affecting the large vessels in the body predominantly the aorta and its main branches. Takayasu aortoarteritis is a rare form of primary systemic vasculitis that appears to be commoner in asia than europe or north america. Leflunomide in takayasu arteritis a long term observational study. The name comes from the doctor who first reported the problem in 1905, dr. The arteries most commonly affected are the branches of the aorta the main blood. Takayasu arteritis is a vasculitis which affects women mainly between. Takayasu arteritis has been associated with different human leucocyte antigen hla alleles in different populations.
A systematic survey in japan during 198284 revealed 2,600 patients of takayasus arteritis, 9 and the incidence was estimated at 2. Takayasu s arteritis is an uncommon condition in which inflammation damages large and mediumsized arteries. The restricted distribution of vessel involvement leads to a pattern of disease that differs markedly from the welldocumented smallmedium vessel vasculitides. Takayasu arteritis is an idiopathic granulomatous vasculitis of the aorta and its main branches and it constitutes one of the more common vasculitides in children. Jan 31, 2020 takayasu s arteritis is a chronic longterm disease in which arteries become inflamed. Takayasus arteritis is recognised worldwide, although it is commoner in southeast asia, africa and south america.
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